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ADVASYL Proteinaceous silk fibres called fibroin Braided Natural Non-Absorbable Surgical Suture

Exceptional control for confidence in gentle tissue approximation

ADVASYL

ADVASYL suture is non-absorbable, sterile, surgical suture composed of an organic protein called fibroin, derived from the domesticated species Bombyx mori (B. mori).

The suture is processed to remove the natural waxes and sericin gum, dyed black and coated with a wax mixture to reduce capillarity and to increase surface lubricity, which enhances handling characteristics, ease of passage through tissue, and knot run-down properties.

The advanced extrusion process of copolymer, the exclusive braiding process and coating system, gives ADVASYL:

  • Excellent handling characteristics

  • Smoother surface for minimal tissue drag & trauma

  • Excellent and consistent knotting strength

  • Superior Wax Coating1

    • Braided suture Minimal tissue drag & trauma
    • Uniform diameter throughout the strand Minimal suture breakage
    • Reduced capillary action Minimal risk of infection transmission
  • OPTIMAL TENSILE STRENGTH
  • Knot pull tensile strength (KgF)3

  • 60% more knot pull tensile strength vs. U.S.P. limit ensure high tensile strength offering strong and secure closure for permanent wound support

REFERENCES:
1 : Handling characteristics of braided suture materials for tight tying - J Appl Bicmater. 1993 Spring; 4(1l:61-5)
2 : Data on file with AMS
3 : Data 0n file with AMS - Bench test done on Silk U.S.P. size-2-0, 45 mm Reverse cutting needle
Premium Needles for consistent Superior Performance
  • DURABLE COAT RETAINS SHARPNESS...PASS AFTER PASS
    Maintains needle sharpness over the duration of procedure, resulting into consistent penetration pass after pass thus less potential for tissue trauma.
  • RIBBED BODY FOR SUPERIOR CONTROL
    For superior grasping and stabilityof needle in needle forceps.
  • CHAMFERING MINIMUM SUTURE DETACHMENT
    Diminishes chances for suture fracturing at the swage, by rounding off the sharp edges of the barrel in the swage area of the needle.
  • ELECTROPOLISHING SMOOTH & BRIGHT
    Makes needle surface free from micro asperities, thus creates ultra sharp edges for lesser tissue drag.

Robust manufacturing process & superior Tyvek packaging

ADVASYL is a non-absorbable sterile surgical suture composed of an organic protein called fibroin. This protein is derived from Bombyx Mori L. (species of the family Bombycidae). Braided silk is coated with wax and is available dyed in logwood black

ADVASYL suture is indicated for use in general soft tissue approximation and/or ligation, including use in ophthalmic and neurological procedures.

Due to the gradual loss of tensile strength which may occur over prolonged period In-vivo, ADVASYL suture should not be used where permanent retention of tensile strength is required. ADVASYL suture is contraindicated in patients with known sensitivities or allergies to Silk.

ADVASYL suture elicits a minimal initial inflammatory reaction in tissues which is followed by gradual encapsulation of the suture by fibrous connective tissue. While silk is not absorbed, progressive degradation of the proteinaceous silk fibre, In-vivo may result in gradual loss of all the suture's tensile strength overtime.

*Mass Absorption: Time in days required for suture to be totally absorbed in the body.

Suture Construction
Suture Color
Effective Tensile Strength Retention
Mass Absorption* (days)
Braided
Black
Gradual Loss Of Tensile Strength over a period of time. Gradual encapsulation of the suture by fibrous connective tissues
Non- Absorbable

PERMANENT WEEK4 WEEK3 WEEK2 WEEK1

ADVASYL suture complies with the requirements of the United States Pharmacopeia requirement for
“Non-Absorbable Surgical Suture” and the European Pharmacopoeia for “Sutures, sterile non-absorbable”.

Features
Benefits
Braided suture
Excellent knot security, excellent first throw hold
Superior wax coating
Uniform diameter throughout the strand provides minimal suture breakage, minimal tissue drag and tissue trauma.
Advanced tipping & mechanical drilling
Ensures minimal suture detachment at the swage point
Advanced Degumming process
Ensures proper separation of the foreign body, sericin from fibroin, to avoid unwanted immunogenic reaction in the body
FULL PORTFOLIO OF ADVASYL
Product IFU Science